Guidelines for Canadian Drinking Water Quality: Guideline Technical Document – Trichloroethylene

Table of Contents

• 1.0 Guideline
• 2.0 Executive Summary
  • 2.1 Health Effects
  • 2.2 Exposure
  • 2.3 Treatment
• 3.0 Identity, Use and Sources in the Environment
• 4.0 Exposure
  • 4.1 Water
  • 4.2 Multi-route Exposure through Drinking Water
  • 4.3 Air
  • 4.4 Food
• 5.0 Analytical Methods
• 6.0 Treatment Technology
  • 6.1 Municipal
  • 6.2 Residential
• 7.0 Kinetics and Metabolism
  • 7.1 Absorption
  • 7.2 Distribution
  • 7.3 Metabolism
  • 7.4 Excretion
• 8.0 Health Effects
  • 8.1 Effects in Humans
  • 8.2 Effects on Experimental Animals and In Vitro
    • 8.2.1 Acute Toxicity
    • 8.2.2 Short-term Exposure
    • 8.2.3 Long-term Exposure and Carcinogenicity
    • 8.2.4 Mutagenicity/Genotoxicity
    • 8.2.5 Reproductive and Developmental Toxicity
    • 8.2.6 Mode of Action of TCE
• 9.0 Classification and Assessment
  • 9.1 Cancer Risk Assessment
  • 9.2 Non-cancer Risk Assessment
• 10.0 Rationale
• 11.0 References
• Appendix A: List of Acronyms

Tables

• Table 1: Carcinogenicity assay in rodents administered TCE by gavage
• Table 2: Carcinogenicity assay in rodents administered TCE by gavage
• Table 3: Carcinogenicity assay in rodents administered TCE by gavage
• Table 4: Carcinogenicity assay in Sprague-Dawley rats administered TCE by inhalation
• Table 5: Incidence of heart malformations in the litters of Sprague-Dawley rats exposed to TCE for the duration of pregnancy