72 Substances identified as being of low concern
These substances were identified for action under the Chemicals Management Plan (CMP). The final screening assessment incorporates results from the Science Approach Document: Ecological Risk Classification of Organic Substances and the Science Approach Document: Threshold of Toxicological Concern (TTC)-based Approach for Certain Substances.
| Final screening assessment | Conclusion on section 64 criteria | Follow-up activities |
|---|---|---|
| HTML | Does not meet | CAS RNs 111-96-6 and 112-49-2: Significant new activity (SNAc) provisions |
Follow-up activities
While exposure to any of the 72 substances is not of concern at current levels, 2 substances (CAS RNs 111-96-6 and 112-49-2) have been identified as having potential health effect of concern. Therefore, there may be a concern if exposure levels were to increase. For this reason, the Government of Canada has applied the SNAc provisions of the Canadian Environmental Protection Act, 1999 (CEPA 1999) to these 2 substances.
Information gathering
Section 71 CMP 2023
In June 2023, a notice was published in the Canada Gazette, Part I: Vol. 157, No. 25 - June 24, 2023, under section 71 of CEPA 1999. This notice applies to 3 substances included in this substance grouping (CAS RNs 793-24-8, 27193-86-8, and 68784-26-9). More information is available on the Information gathering with respect to certain substances under the Chemicals Management Plan web page.
| Date | Activity |
|---|---|
| June 24, 2023 | Publication in Canada Gazette, Part I, of a notice under section 71 of CEPA 1999. |
| August 3, 2022 | Publication in the Canada Gazette, Part II: Vol. 156, No. 16 of an order amending the Domestic Substances List (DSL) to apply the SNAc provisions of the CEPA 1999 to CAS RNs 111-96-6 and 112-49-2. |
| November 3, 2018 | Publication in the Canada Gazette, Part I: Vol. 152, No. 44 and start of 60-day public comment period on a notice of intent to amend the DSL to apply the SNAc provisions of CEPA 1999 to CAS RNs 111-96-6 and 112-49-2. |
| November 3, 2018 | Publication of the final screening assessment. The related notice was published in the Canada Gazette, Part I: Vol. 152, No. 44. |
| June 17, 2017 | Publication and start of 60-day public comment period on the draft screening assessment (including follow-up activities for 36 of the 74 substances). The related notice was published in the Canada Gazette, Part I: Vol. 151, No. 24. |
Background
Combining the results from both approaches, 75 substances were identified to be of low concern for human health and ecological risk. One substance (CAS RN 118-96-7) was later found to be associated with an international classification for carcinogenicity based on empirical data with positive results, thereby excluding it from the TTC-based approach. This substance was assessed in the Final Screening Assessment for the Rapid Screening of Substances with Limited General Population Exposure.
Also, as a result of new information on uses and volumes submitted pursuant to a CEPA 1999 section 71 notice, 2 additional substances (CAS RNs 4979-32-2 and 94270-86-7) that were included in the draft of this screening assessment have been removed for further assessment due to potential human health concerns. These substances are being assessed as a part of the Benzotriazoles and Benzothiazoles Group.
Page details
- Date modified: