Impact of COVID-19 in adults with chronic conditions: Emergency department visits

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Organization: Public Health Agency of Canada

Published: 2022-10-21

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Overview

COVID-19 has had a substantial impact on people in Canada. It has affected people’s health and strained the healthcare system. As of early May 2022, more than 3.7 million SARS-CoV-2 infections, confirmed by polymerase chain reaction, have been reported in Canada.

This fact sheet describes the demographics, health characteristics, and outcomes of adults during their first documented emergency department visit (EDV) with a COVID-19 diagnosis. We also look at the relationship between severe EDV outcomes (ie., hospital admission, transfer to an acute care facility, or death) and sex, age and selected chronic conditions.

We've limited our analysis to adults (aged 20+) visiting select emergency departments in Canada between January 1, 2020, and March 31, 2021. Please refer to the technical notes for data sources, methods, and limitations.

Summary of characteristics and outcomes

We analyzed data for 97,939 adult EDVs with a confirmed (69.3%) or suspected (30.7%) COVID-19 diagnosis. Of these:

We examined the data to determine which patients had any of 18 chronic conditions listed in Figure 3. About 22.3% had at least 1 chronic condition.

The most common chronic conditions documented in their acute care hospitalizations over the past 10 years were:

With respect to healthcare use over the past 6 months:

In regards to EDV outcomes (Figure 1):

Characteristics of patients with severe outcomes

Severe outcomes include being admitted to hospital, transferred to an acute care facility, and death. Compared to people with other outcomes, those who had severe outcomes were more likely to:

Severe outcomes increased with age from 5.7% (20 to 34 year olds) to 69.1% (80+ year olds) [Figure 2]. Across all age groups, males were more likely than females to have a severe outcome.

For all 18 of the chronic conditions we examined, adults with severe outcomes were more likely to have the condition than adults with other outcomes (Figure 3). In fact, those with severe outcomes were 3.5 times more likely to have at least 1 chronic condition (49.1% versus 13.9%).

The more chronic conditions a patient had, the more likely they were to have a severe outcome. The percentage of adults experiencing these serious outcomes increased from 15.7% for those with no known chronic conditions, to 71.1% for those with 4 or more (Figure 4). This relationship was observed across all age groups.

What you can do to reduce the rate of infections and severe disease

For more information on COVID-19, please visit the Government of Canada's main COVID-19 page.

Figure 1. Distribution of outcomes for adults (age 20+) during their first emergency department visit with a confirmed or suspected COVID-19 diagnosis, Canada, January 1, 2020, to March 31, 2021 (N = 97,939)
Figure 1. Text version below.
Figure 1: Text description
Visit outcomes Percentage of patients
Discharged home 73.2
Transferred to non-acute care facility 1.6
Admitted or transferred to acute care facility 23.8
Died 0.2
Transferred to other ambulatory care or patient left 1.2

Source: Canadian Institute for Health Information's National Ambulatory Care Reporting System.

Notes:

Figure 2. Percent of adults (age 20+ years) who were admitted, transferred to an acute care facility, or died during their first emergency department visit with a confirmed or suspected COVID-19 diagnosis by age group and sex, Canada, January 1, 2020, to March 31, 2021 (N = 97,939)
Figure 2. Text version below.
Figure 2: Text description
Age group (years) Percent admitted, transferred to an acute care facility, or died

Both sexes

Aged 20 years and older 24.0
Aged 20 to 34 5.7
Aged 35 to 49 10.9
Aged 50 to 64 22.6
Aged 65 to 79 45.2
Aged 80 and older 69.1

Males

Aged 20 years and older 27.0
Aged 20 to 34 6.2
Aged 35 to 49 13.3
Aged 50 to 64 26.2
Aged 65 to 79 49.0
Aged 80 and older 70.9

Females

Aged 20 years and older 21.1
Aged 20 to 34 5.2
Aged 35 to 49 8.7
Aged 50 to 64 18.7
Aged 65 to 79 40.7
Aged 80 and older 67.4

Source: Canadian Institute for Health Information's National Ambulatory Care Reporting System.

Notes:

Technical notes

Data sources

Canadian Institute for Health Information:

Methodology

We extracted EDVs with a COVID-19-related diagnosis occurring between January 1, 2020, and March 31, 2021, from NACRS. To identify these EDVs, we searched the main and other problem fields of visit records for International Statistical Classification of Diseases and Related Health Problems, 10th revision, Canada (ICD-10-CA) diagnosis codes introduced to capture COVID-19 (U07.1, U07.2, U07.3, U07.4, U07.5). For visits containing a subset of the full NACRS dataset with no main or other problem data, we also searched the discharge diagnosis fields. We retained for analysis all first visits for a person that had a confirmed (U07.1) or suspected (U07.2) COVID-19 diagnosis. People were identified using birth year, province or territory issuing the health card number, and anonymized health card number.

Figure 3. Percent of adults (age 20+ years) with chronic conditions at their first emergency department visit with a confirmed or suspected COVID-19 diagnosis by visit outcome, Canada, January 1, 2020, to March 31, 2021 (N = 97,939)
Figure 3. Text version below.
Figure 3: Text description
Chronic conditions Percent with chronic condition

All adults, all outcomes

Cancer 3.6
Chronic obstructive pulmonary disease 2.7
Asthma 1.3
Diabetes mellitus 9.4
Hypertension 11.8
Ischemic heart disease 5.3
Heart failure 3.3
Stroke 2.0
Dementia 1.9
Schizophrenia 0.7
Epilepsy 0.7
Multiple sclerosis 0.1
Parkinsonism 0.3
Rheumatoid arthritis 0.3
Gout and other crystal arthropathies 0.6
Osteoarthritis 3.4
Osteoporosis 0.7
Obesity 1.8
1+ condition(s) 22.3

Adults admitted, transferred to an acute care facility, or died

Cancer 8.1
Chronic obstructive pulmonary disease 7.6
Asthma 2.4
Diabetes mellitus 23.2
Hypertension 29.4
Ischemic heart disease 12.3
Heart failure 10.2
Stroke 5.6
Dementia 6.2
Schizophrenia 1.4
Epilepsy 1.4
Multiple sclerosis 0.3
Parkinsonism 1.1
Rheumatoid arthritis 0.7
Gout and other crystal arthropathies 1.8
Osteoarthritis 7.4
Osteoporosis 2.0
Obesity 3.3
1+ condition(s) 49.1

Adults with other outcomes

Cancer 2.2
Chronic obstructive pulmonary disease 1.2
Asthma 0.9
Diabetes mellitus 5.1
Hypertension 6.2
Ischemic heart disease 3.1
Heart failure 1.2
Stroke 0.9
Dementia 0.6
Schizophrenia 0.4
Epilepsy 0.4
Multiple sclerosis 0.1
Parkinsonism 0.1
Rheumatoid arthritis 0.2
Gout and other crystal arthropathies 0.2
Osteoarthritis 2.2
Osteoporosis 0.2
Obesity 1.3
1+ condition(s) 13.9

Source: Canadian Institute for Health Information's National Ambulatory Care Reporting System and Discharge Abstract Database.

Notes:

Figure 4. Percent of adults (age 20+ years) who were admitted, transferred to an acute care facility, or died during their first emergency department visit with a confirmed or suspected COVID-19 diagnosis by age group and chronic condition count, Canada, January 1, 2020, to March 31, 2021 (N = 97,939)
Figure 4. Text version below.
Figure 4: Text description
Age group (years) Percent admitted, transferred to an acute care facility, or died

0 chronic conditions

Aged 20 years and older 15.7
Aged 20 to 34 4.9
Aged 35 to 49 9.3
Aged 50 to 64 18.6
Aged 65 to 79 36.0
Aged 80 and older 61.5

1 chronic condition

Aged 20 years and older 40.2
Aged 20 to 34 21.3
Aged 35 to 49 22.4
Aged 50 to 64 31.4
Aged 65 to 79 47.2
Aged 80 and older 67.1

2 chronic conditions

Aged 20 years and older 53.6
Aged 20 to 34 30.0
Aged 35 to 49 35.2
Aged 50 to 64 41.8
Aged 65 to 79 52.7
Aged 80 and older 70.7

3 chronic conditions

Aged 20 years and older 61.9
Aged 20 to 34 35.7
Aged 35 to 49 37.4
Aged 50 to 64 45.3
Aged 65 to 79 60.6
Aged 80 and older 75.6

4 or more chronic conditions

Aged 20 years and older 71.1
Aged 20 to 34 44.4
Aged 35 to 49 48.9
Aged 50 to 64 54.9
Aged 65 to 79 70.3
Aged 80 and older 78.2

Source: Canadian Institute for Health Information's National Ambulatory Care Reporting System and Discharge Abstract Database.

Notes:

We obtained information on chronic conditions by linking EDVs to DAD acute care hospital separations occurring within the past 10 years. For the majority of conditions, we used Canadian Chronic Disease Surveillance System (CCDSS) validated case definitions with some exceptions to address gestational diabetes and hypertension. To determine if a person had a history of cancer (C00-C97) or obesity (E66), we searched all 25 diagnosis fields. In total, 18 chronic conditions were examined (see Figure 3 for a complete list). We also obtained information on number of EDVs and acute care hospitalizations within the past 6 months by linking to NACRS and DAD, respectively.

All reported comparisons and associations are statistically significant at an alpha level of 0.05 (two-tailed). We used the chi-square test to compare proportions and test for associations, and the t-test to compare means.

Data limitations

Some important data limitations should be acknowledged.

First, NACRS does not capture all EDVs occurring in Canada. EDVs occurring in New Brunswick, Newfoundland and Labrador, Northwest Territories, and Nunavut are not included, and coverage is incomplete for British Columbia, Saskatchewan, Manitoba, Nova Scotia, and Prince Edward Island. Further, EDVs occurring in Quebec are not available to the Public Health Agency of Canada.

Second, since the prevalence of chronic conditions is based on past acute care hospitalizations, it is likely underestimated. Among the chronic conditions examined in this fact sheet, only diabetes mellitus is routinely coded when documented. For the other chronic conditions, mandatory reporting is based on criteria like the condition increasing a patient's length of stay, or the condition co-occurring with other specific conditions that have been coded. In addition, some adults with chronic conditions may not have past acute care hospitalizations. Consequently, direct comparisons with CCDSS prevalence estimates should not be made because the CCDSS uses additional data sources, such as physician billing claims and prescription drug records, to identify chronic conditions.

Acknowledgements

The data sources for this fact sheet are made possible through collaborations between the provinces and territories, and the Canadian Institute for Health Information. Results and interpretations reported in this fact sheet are those of the Public Health Agency of Canada. No endorsement by the provinces and territories or the Canadian Institute for Health Information is intended or inferred.

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