Evidence brief on attitudes and acceptance of COVID-19 booster doses

January 2022

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Table of contents

Introduction

What is the evidence on the knowledge, attitudes, and behaviors related to booster (third/additional) doses of the COVID-19 vaccine in Canada, Australia, New Zealand, UK, and the US?

Canada has one of the highest vaccination rates of the primary series (2 doses) of COVID-19 in the world, with 82.8% of those over the age of 5 fully vaccinatedFootnote 1. The UK and Australia approved COVID-19 booster doses for those over 18 years old in September and October 2021, respectivelyFootnote 2Footnote 3. In November 2021 booster doses of COVID-19 vaccines were approved for those over 18 in Canada, New Zealand, and the USFootnote 4Footnote 5Footnote 6.

Understanding the facilitators, barriers, and hesitancy to accept or refuse COVID-19 booster doses among those who have already accepted two doses is important for encouraging recommended vaccination among both partially vaccinated and unvaccinated populations in the face of waning immunity and more transmissible variants. This evidence brief summarizes literature on the intention to accept a booster dose of vaccine among the general population and factors associated with the intention to accept or reject additional doses. The focus of this evidence brief is on the Five Eyes countries (Canada, Australia, New Zealand, UK, and US) as these countries tend to have similar trends. This brief contains literature up to January 31, 2022.

Key points

There were 14 studies identified that evaluated attitudes and acceptance of a COVID-19 booster dose in Canada (n=4), UK (n=3), US (n=5), Canada and US (n=1) and globally (13 countries including Australia, Canada, UK, and US, n=1) (Table 1). Ten of the studies were conducted since the approval of the COVID-19 booster dose in their respective countries and the remaining 4 were conducted prior to the approvals in early to mid-2021.

Barriers and facilitators to accepting a COVID-19 booster were similar to accepting first and second doses of the vaccineFootnote 15.

COVID-19 booster attitudes in the general public were explored in nine studies (Table 1). Six of the studies were conducted since the approval of booster doses in their respective countries.

Overview of the evidence

Fourteen studies evaluating the attitudes of the general public toward booster doses (third doses) of COVID-19 vaccine were identified and included in this review. Of these, two are preprints and eight are reports which have not completed the peer-review process. The publications reporting on third dose vaccine attitudes are all observational studies (e.g., cross-sectional study using an online survey).

A formal risk of bias evaluation was not conducted. Across observational studies the reliability of the outcome is based on obtaining a representative sample of the target population that is sufficiently large to obtain a representative spectrum of results. Studies frequently did not demonstrate the representativeness of their samples to the target population in both grey literature or government reports published online (not indexed), preprints, and published journal articles. Longitudinal studies where a population was sampled more than one time to monitor changes in vaccine intentions and attitudes over time were the strongest observational study design identified. Most observational studies were cross-sectional online surveys at a single point in time. These study designs are at moderate/high risk of bias and thus, are considered medium-low quality depending on the sample size and whether the sample represents the target population as well as how well the survey tool can measure the outcome(s) of interest (e.g., was it informed by formative research, validated and pretested prior to implementation). For most of the included studies the outcomes are self-reported, which can be biased by response and social desirability biases. Other biases considered in these studies include response rate and missing data. While there are many studies that show similar trends, the conclusions could change with additional research, larger sample size, different sampling strategies, data collection tools, and progression through the pandemic.

A key knowledge gap in this research are studies that address booster dose intentions and reasons for hesitancy and refusal rates in high-risk and underserved populations, and studies which identify factors that would encourage individuals to receive a booster dose. The majority of studies used online surveys, and to a lesser extent telephone surveys, which may limit participation from segments of population due to lack of access. Given the variable access to booster doses, understanding intention to vaccinate and hesitancy for accepting a booster dose remains crucial to encouraging vaccination in the face of waning immunity and more transmissible variants.

COVID-19 booster intentions and attitudes of the general public

Attitudes and acceptance of a booster dose of the COVID-19 vaccine in the general public were explored in 14 studies. There were four studies specific to Canada, three in the UK, five in the US, one that looked at both Canada and the US, and one global study that included Australia, Canada, UK, and US. High level points from all studies are listed below followed by more detailed outcomes (Table 1).

Intention to accept COVID-19 boosters decreased between late 2021 and early 2022Footnote 8Footnote 11Footnote 12.

Barriers and facilitators to accepting a COVID-19 booster were similar to accepting first and second doses of the vaccineFootnote 15.

Attitudes towards COVID-19 boosters

Methods

Publications and Preprints

A daily scan of the literature (published and pre-published) is conducted by the Knowledge Synthesis team in the Emerging Science Group, Public Health Agency of Canada. The scan has compiled COVID-19 literature since the beginning of the outbreak and is updated daily. Searches to retrieve relevant COVID-19 literature are conducted in Pubmed, Scopus, BioRxiv, MedRxiv, ArXiv, SSRN, Research Square, and and cross-referenced with the COVID-19 information centers run by Lancet, BMJ, Elsevier, Nature and Wiley. The cumulative scan results are maintained in a Refworks database and an excel list that can be searched. Targeted keyword searching is conducted within these databases to identify relevant citations on COVID-19 and SARS-COV-2. Search terms used included: (“vaccin*” or “immuni*”) and (“third dose*” or “booster”). This review contains research published up to January 31, 2022.

Grey Literature

A grey literature search was conducted to compliment the database search. The grey literature search focused on targeted governmental and academic institutions. A detailed list of websites searched is available upon request. The grey literature search was last updated on January 31, 2022.  

Each potentially relevant reference was examined to confirm it had relevant data and relevant data was extracted into the review. 

Acknowledgements

Prepared by: Tricia Corrin and Austyn Baumeister, National Microbiology Laboratory Emerging Science Group, Public Health Agency of Canada.

Editorial review, science to policy review, peer-review by a subject matter expert and knowledge mobilization of this document was coordinated by the Office of the Chief Science Officer: ocsoevidence-bcscdonneesprobantes@phac-aspc.gc.ca

Evidence tables

Table 1. Evidence of attitudes and acceptance of a booster dose of the COVID-19 vaccine in the general public (n=14)

Study Method Outcomes
Canada (n=5)

INSPQ (2021)Footnote 7Footnote 25
grey literature

Longitudinal study

Canada
Jan 2022

Analysis of the acceptability of vaccination against COVID-19 was evaluated using an online survey of adults and HCWs in Quebec. Number of participants was not clearly stated (~3300 each collection period). Articles in French. There were multiple collection periods:
Jan 11th, 2022
Jan 25th, 2022

  • 42% of respondents have received three doses.
  • Most (70%) of respondents who have had two doses intend to get a third dose, 13% do not intend to, and 10% were unsure.
  • Not intending to receive a third dose among those with two doses was higher among men, those aged 25-44, those with less education (college or less), and those living in small towns (smaller than 10,000) compared to their counterparts.
  • 80% agreed that a third dose should be offered to all people aged 18+, 14% disagreed, and 6% were unsure.
  • 63% would be in favor of Canada sending vaccines to developing countries before offering third doses to Canadians, 29% disagreed, and 9% were unsure.

Ipsos (2022)Footnote 8
grey literature

Cross-sectional study

Canada
Jan 2022

An online survey of 1001 adults across Canada (18+) were recruited from the Ipsos I-say panel as well as non-panel sources to understand vaccination in the time of Omicron.
  • 77% would receive a third dose without hesitation (or have already received their third dose), and 23% were hesitant. This was up from a survey conducted in May 2021 where 34% of those aged 18-34 would not get a third dose, followed by 28% of those aged 35-54, and 10% of those aged 55+.
  • 68% and 76% agreed that getting a third dose will reduce the likelihood of getting COVID-19 and the likelihood of ending up in hospital, respectively. 
  • 56% were concerned about long term side-effects from a third dose and this concern was more prevalent among younger respondents compared to older respondents (66% among those aged 18-34, 57% in those aged 35-54, and 47% among those aged 55+).

Angus Reid (2021)Footnote 9Footnote 22Footnote 23
grey literature

Longitudinal study

Canada
Sep 2021 – Jan 2022

Intentions for getting a third dose of the COVID-19 vaccine were analyzed in a sample of the general population using an online survey across a representative randomized sample who are members of the Angus Reid Forum.

Sep 29 – Oct 3, 2021 (n=5011)
Jan 7-1, 2022 (n=3375)
Jan 7-12, 2022 (n=5002)

Jan 2022

  • 69% of those who have received three doses disagreed with the statement that it is time to end restrictions and let people self-isolate if they are at risk (5% unsure and 25% agreed). This was higher than those who have not been vaccinated yet (89% agreed) or the average across Canada (39% agreed).
  • Most respondents who received three doses felt that restrictions in their community were about right (44%) compared to the 85% of unvaccinated who felt restrictions were too strict. 
  • 54% of third dose recipients believed that they will be exposed to and infected by Omicron no matter what they do.
  • 31% of those who received three doses thought if they got COVID-19 they would have relatively mild symptoms, 52% thought it would be serious but manageable, 13% thought it would be very severe, and 4% thought it may be deadly. In comparison only 6% of the unvaccinated and 14% of those with two doses believed if they caught COVID-19 it would be severe or deadly.

Sep-Oct 2021

  • Among those who had already received at least one dose (n=4527), 62% reported they would get a booster vaccine as soon as it was available to them, 20% would get one but would prefer to wait, 9% would not get a booster, 8% were not sure, and 1% have already received a booster.
  • Canadians aged 18-24 (15%) and 35-44 (13%) were the least likely to get a booster compared to the average of 9%. In contrast, 75% of those aged 65+ would get a booster as soon as possible.
  • 15% of past voters for the Conservative Party of Canada and 10% of past voters for the Bloc Québécois report they will not get a booster compared to 2% of past Liberal voters and 3% of past NDP voters.

Leger (2021)Footnote 21Footnote 26Footnote 27
grey literature

Longitudinal study

Canada & US
Aug 2021-Jan 2022

An online survey of Canadian and American adults (18+) was conducted to evaluate vaccine perceptions and intentions to vaccinate. Canadian data is summarized here and data from the US is found in the US section.

Aug 2021, 1,515 Canadians, 1,005 Americans
Dec 2021, 1,547 Canadian, 1,004 Americans
Jan 2022, 1,547 Canadian, 1,014 American

Jan 2022

  • 81% believed that getting vaccinated, including receiving additional doses of the vaccine when necessary is effective for providing protection against COVID-19.
  • Belief in the effectiveness of vaccination including receiving booster doses was highest in those aged 55+, those living in sub-urban areas, and those already fully vaccinated (two doses).

Dec 2021

  • 78% were in favour of speeding up the introduction of third doses to certain populations and 22% were opposed.
  • Support for speeding up the introduction of third doses was higher in Quebec, in those aged 55+, and those already fully vaccinated (two doses).

Aug 2021

  • 58% agreed that if studies show that a third dose is required for those that initially received AstraZeneca they would get a third dose, 7% felt comfortable as they were, and 35% did not receive AstraZeneca.

Nanos (2021)Footnote 10Footnote 28
grey literature

Longitudinal study

Canada
Sep-Dec 2021

A hybrid telephone and online survey of adults (18+) across Canada was conducted to evaluate interest in receiving a third dose of the COVID-19 vaccine.

Sep-Oct 2021 (n=1017)
Dec 2021 (n=1005)

Dec 2021

  • 89% would receive a third dose when it becomes available to them, 9% would not, and 2% were unsure. Intention to get a third dose is up from Sep-Oct 2021.
  • By province the highest level of interest to receive a third dose was found in the Atlantic Canada (93.3%), QC (90.1%), ON (90%), BC (85.2%), and the Prairies (82.5%).
  • Those aged 55+ (96.6%) were more interested in a third dose compared to those aged 35-54 (88.1%) and 18-34 (76.5%).
  • Men were slightly more interested in receiving a booster compared to women (89.7% vs 86.8%).

Sep-Oct 2021

  • 84% were interested in getting a third dose, 10% were not interested, 3% were unsure, and 3% were unvaccinated.
  • By province the highest level of interest was found in BC (87.9%), ON (86.1%), QC (82.7%), Atlantic Canada (81.3%), and Prairies (78.5%).
  • Those aged 55+ (89.8%) were more interested in a third dose compared to those aged 35-54 (83.2%) and 18-34 (76.1%).
  • Men were slightly more interested in receiving a booster compared to women (84.2% vs 83.5%).

United Kingdom (n=3)

Paul (2022)Footnote 17
preprint

Cross-sectional study

UK
Nov-Dec 2021

Factors associated with COVID-19 booster vaccine intentions were evaluated in 22,139 fully vaccinated (two doses) adults in the UK.

  • 4% of the weighted sample were unwilling to receive a COVID-19 booster vaccine and 4% were uncertain.
  • Those who were initially uncertain about receiving a vaccine (first and second doses) were more likely to be uncertain or unwilling to receive a booster (uncertain: RR 4.92, 95%CI: 2.98-8.11; unwilling: RR 5.29, 95%CI: 3.07- 9.09) compared to those who were initially willing. Initial unwillingness was also associated with a higher risk of booster uncertainty and unwillingness (uncertain: RR 6.40, 95%CI: 3.94-10.41; unwilling: RR 11.29, 95%CI: 6.79-18.78).
  • Low compliance with COVID-19 guidelines during strict restriction periods was a predictor of unwillingness (RR 2.45, 95%CI: 1.65-3.65) and uncertainty (RR 1.51, 95%CI: 1.04-2.19). Low levels of current stress about getting or becoming seriously ill from COVID-19 also predicted unwillingness (RR 1.91, 95%CI: 1.19-3.07) and uncertainty (RR 1.80, 95%CI: 1.19-2.72) about boosters.
  • Unwillingness to receive a booster was associated with being aged 18-29 (RR 5.74, 95%CI: 2.82-11.68), having less education (RR 2.50, 95%CI: 1.31-4.79), and being healthy (RR 1.52, 95%CI: 1.00-2.30) compared to those who were older, had more education, and longer-term physical health conditions. These trends were also seen with those who were uncertain about receiving a booster.
  • Three additional predictors of uncertainty were also identified. Those who were uncertain about receiving a booster were more likely to be unemployed (RR 3.25, 95%CI: 2.11-5.02) have lower levels of income (RR 2.43, 95%CI: 1.06-5.59), and have low self-reported knowledge of COVID-19 (RR 1.78, 95%CI: 1.19-2.67).

Office for National Statistics (2021)Footnote 20
grey literature

Cross-sectional study

UK
Sep 2021

In this COVID-19 Vaccine Opinions Study (VOS) respondents who previously reported being vaccine hesitant in the Opinions and Lifestyle Survey (OPN) and consented to follow-up (n=2480) were asked about motivations and barriers to vaccination.

  • 6% of all previously hesitant respondents reported that they were unlikely to receive a booster dose.
  • 50% of previously hesitant respondents who received two doses of the vaccine (n=750 total) were likely to get the booster, 11% were neither likely nor unlikely, 22% were fairly unlikely, 13% were unsure, and 4% did not want to say.
  • Those aged 30-49 were more unlikely (26%) to get a booster dose compared to 16% of those aged 18-29 and 17% of those aged 50-69.
  • The main reasons for being unlikely to accept a booster dose included believing that a booster dose would not offer more protection (60%), the first and second dose would keep them safe (47%), and worry about the long term effects (46%).
  • Those who were not likely to get a booster indicated they will not be motivated to get a booster (55% reported no potential informational and socio-psychological motivators, 44% reported no motivation to get access to daily activities, and 63% reported no interest in vaccines incentives for getting a booster dose).
  • Top motivators across all categories included helping life return to normal (34%), making it easier to go abroad (30%), to protect others from COVID-19 (26%), to protect themselves (23%), and vouchers or discounts (23%).
  • Of those that would be motivated by vouchers, 97% reported discounts for food or clothes would make them more likely to get a booster.

Office for National Statistics (2021)Footnote 12Footnote 18Footnote 29Footnote 30Footnote 31Footnote 32Footnote 33Footnote 34Footnote 35Footnote 36Footnote 37Footnote 38Footnote 39Footnote 40
grey literature

Longitudinal study

UK
Jul 2021-Jan 2022

Intention to accept a booster dose of the COVID-19 vaccine was collected as part of the online Opinions and Lifestyle Survey.

2021
Jul 28 – Aug 1 (n=3,860)
Aug 11 – 15 (n=3,130)
Aug 18 – 22 (n=2,900)
Aug 25 – Sep 5 (n=3,170)
Sep 8 – 19 (n=3,350)
Sep 22 – Oct 3 (n= 3,140)
Oct 6 – 17 (n= 3,760)
Oct 20 – 31 (n= 4,210)
Nov 3- 14 (n=1,860)
Nov 18 – 28 (n= 1,390)
Dec 1 – 12 (n=1080)
Dec 15 – 19 (n= 670)
Dec 15 - Jan 3 (n = 4,700)
2022
Jan 6 - 16 (n= 3,290)

January 2022

  • Among all respondents, 89% felt booster vaccines were important to slow the spread of COVID-19, 7% were undecided, and 4% believed they were not important.
  • Among those who have received two doses of vaccine, 72% were likely to get a booster dose (down 17% since December), 13% were unlikely (up 7%), 10% were neither unlikely or likely (up 6%), 4% were unsure (up 3%), and 2% preferred not to say (up 1%).
  • Top reasons among those who were unlikely to receive a booster dose were that the primary series will keep them safe (47%), the booster dose will not offer extra protection (39%), and worry about a bad reaction to a booster dose (27%).
  • 75% were likely to get a booster dose for COVID-19 at the same time as their flu shot, 13% were neither likely nor unlikely, and 5% were fairly unlikely.
  • Older respondents were more likely agree that booster vaccines are important to slow the spread of COVID-19 and to be likely to get a booster dose.
  • More men than women were likely to get a booster dose (77% vs 67%).
  • 87% of those who were clinically extremely vulnerable were likely to get a booster dose.

December 2021

  • Among those who have already received two doses of vaccine, 89% were likely to get a booster dose (up 2% from November), 6% were unlikely (up 1%), 4% were neither unlikely to likely (down 2%), 1% were unsure (no change), and 1% preferred not to say (no change).
  • Major reasons for hesitancy included not believing a booster would offer more protection (55%), believing that the first and second dose will keep them safe (34%), and worry about a bad reaction to the booster (33%).

November

  • Among those who have already received two doses of vaccine, 91% were likely to get a booster (down 1% from October), 5% were unlikely (down 1%), 4% were neither unlikely to likely (no change), 1% were unsure (no change), and 1% preferred not to say (no change).
  • Major reasons for being either very or fairly unlikely to get a booster included believing that the first and second dose will keep them safe (59%), not believing a booster would offer more protection (49%), and worry about long term effects (33%).
  • 83% would be likely or very likely to get a booster with their flu vaccine and 9% would be unlikely or very unlikely.

October

  • Among those who have already received two doses of vaccine, 92% were likely to get a booster (up 1% since September), 4% were unlikely (no change), 2% were neither unlikely to likely (up 1%), 1% were unsure (down 1%), and less than 1% preferred not to say (no change).  
  • Major reasons for being unlikely to get a booster included believing that the first and second dose will keep them safe (46%), not believing a booster would offer more protection (39%), and believing boosters should be offered to others first (31%).
  • 81% would be likely or very likely to get a booster with their flu vaccine and 9% would be unlikely or very unlikely.

September

  • Among those who have already received two doses of vaccine, 91% are very likely to get a booster (up 3% since August), 4% were unlikely (down 2%), 3% were neither unlikely to likely (no change), 2% were unsure (down 2%), and less than 1% preferred not to say (no change).  
  • Major reasons for being unlikely to get a booster included believing that the first and second dose will keep them safe (63%), not believing a booster would offer more protection (42%), and believing boosters should be offered to others first (28%).
  • 82% would be likely to get to get their booster at the same time as the flu vaccine.

August

  • 88% were likely to get a booster vaccine if it was offered (down 1% from July/August), 3% were neither likely nor unlikely (no change), 6% were unlikely (up 1%), 4% were unsure (up 1%), and less than 1% preferred not to say (no change).
  • 85% would be likely to get a booster with their flu vaccine.

July - August

  • 89% were likely to get a booster vaccine if it was offered, 3% were neither likely nor unlikely, 5% were unlikely, 3% were unsure, and 1% preferred not to say.
  • 85% would be likely get a booster with their flu vaccine.
US (n=6)

Leger (2021)Footnote 21Footnote 26Footnote 27
grey literature

Longitudinal study

Canada & US
Aug 2021-Jan 2022

An online survey of Canadian and American adults (18+) was conducted to evaluate vaccine perceptions and intentions to vaccinate. Data from the US is summarized here and Canadian data is in the Canada section.

Aug 2021, 1,515 Canadians, 1,005 Americans
Dec 2021, 1,547 Canadians, 1,004 Americans
Jan 2022, 1,547 Canadians, 1,014 American

January 2022

  • 63% believed that getting vaccinated (including receiving additional booster doses of the vaccine when necessary) was effective at providing protection from the virus.

December 2021

  • 63% were in favor of speeding up the introduction of third doses to certain populations and 37% were opposed.

Lee (2021)Footnote 14
preprint

Cross-sectional study

US
Aug-Nov 2021

COVID-19 booster vaccine attitudes and behaviors among 3,668 university students and staff at the University of Southern California were evaluated using an online survey.

Willingness to receive a booster was coded as “unwilling” (never) and “willing” (any response other than “never”).

  • 96.2% were willing to receive a COVID-19 booster at least once per year, and 64% were willing to get boosters as often as necessary.
  • In bivariate analyses, those without prior COVID-19 infections had higher odds of booster willingness compared to those with self-reported prior COVID-19 infection (OR 1.99, 95%CI: 1.24-3.07).
  • In multivariate analyses, Asians had higher odds of booster willingness (at least one COVID-19 booster) compared to Whites (OR 2.45, 95%CI: 1.46-4.18). A higher trust in science was also associated with having higher odds of booster willingness (OR 8.73, 95%CI: 6.29-12.30).

Hahn (2022)Footnote 13

Longitudinal study

US
Nov 2020-Sep 2021

Residents from remote communities in Alaska participated in three online surveys to evaluate residents’ early vaccine acceptance, vaccine uptake and motivations, risk perceptions and knowledge about COVID-19 vaccines, and likelihood of getting a booster vaccine.

Survey 1: Nov-Dec 2020 (n=107)
Survey 2: Mar 2021 (n=508)
Survey 3: Sep 2021 (n=405)

Only results on acceptability of a booster vaccine are captured from survey 3.

  • Of those who had received two doses of a COVID-19 vaccine (n = 340), 79.7% said they would probably or definitely accept a COVID-19 booster when it became available.
  • Most respondents (68-75%) would probably or definitely encourage their parents, older family members, and friends to get the booster.
  • 88% did not have concerns about the COVID-19 booster. Of the 12% who did, the concerns included chronic health issues, unknown side effects, and side effects from previous COVID-19 vaccinations.

Yadete (2022)Footnote 16

Cross-sectional study

US
Jul 2021

COVID-19 vaccine booster hesitancy and its associated factors were evaluated using an online survey. The survey included 2,138 adults from across the US.
  • 61.8% were willing to take the booster dose and 38.2% were booster dose hesitant.
  • Those who had already received a primary dose of COVID-19 vaccine were more likely to accept booster doses (OR 3.32, 95%CI: 2.20–5.01).
  • Parents who were willing to have their children vaccinated (OR 10.3, 95%CI: 6.78–15.77) and being a Democrat (OR 1.90, 95%CI: 1.17-3.10) were more likely to accept a booster dose. Other factors associated with booster dose acceptability included living with a vulnerable family member, having COVID-19 positive friends or family members, and having pre-existing conditions.
  • Significant factors for those who were hesitant to accept a booster included being younger, female, unvaccinated, having no religious affiliation, never been married, uninsured, being less educated, having little trust in COVID-19 vaccine information, and living in a southern region of the nation.
  • The mean scores of vaccine confidence index and vaccine literacy were lower among the hesitant group compared to the non-hesitant group.
  • Those who would accept a booster were more likely to agree (~85%) with the statements “vaccines are important for my health” and “vaccines are effective” compared to those who were hesitant (~47%).

Lennon (2022)Footnote 19

Cross-sectional study

US
May-Jun 2021

Attitudes towards COVID-19 booster, influenza, and a hypothetical combination influenza-COVID-19 booster vaccines were evaluated using an online survey of 12,887 adults from across the US.

  • As a stand-alone vaccine, 45% of respondents would accept a COVID-19 booster and 58% would accept an influenza vaccine. For a combination influenza-COVID-19 vaccine, overall acceptance was 50%.
  • African Americans respondents were less willing to accept the COVID-19 booster alone (OR 0.67, p<0.01) or a combination influenza-COVID-19 booster (OR 0.60, p<0.05) compared to White respondents.
  • There was lower acceptance for the COVID-19 booster alone or a combination influenza-COVID-19 boosters among female, Black/African American, Native American/American Indian, and rural respondents. Higher acceptance was found among those who were older, identified as Democrat, had higher education, and those who have previously usually accepted the annual influenza vaccine.

Pal (2021)Footnote 24

Cross-sectional study

US
Feb-Mar 2021

An online survey was used to assess vaccine hesitancy and attitudes toward a potential additional booster dose of COVID-19 vaccines among 1,358 healthcare workers (HCWs) across the US.

Those who had received both doses or were planning to receive both doses of the vaccine were labelled as the vaccine non-hesitant group and those who did not accept either dose or were waiting or unsure, were labelled as the vaccine-hesitant group.

  • 63.6% were worried that current vaccination may not be effective against new strains and that additional booster doses or new vaccines may be required. These concerns did not differ between the vaccine-hesitant and non-hesitant groups (68.8% vs 63.1%).
  • Overall acceptance for a hypothetical yearly booster vaccine to maintain immunity was 83.6%. Acceptance of a hypothetical annual booster dose was much lower among the vaccine-hesitant group (13.8%) compared to the non-hesitant group (89.9%). 
Global (n=1)

Ipsos (2021)Footnote 11
grey literature

Cross-sectional study

Global (Canada, Australia, Brazil, China, France, Germany, Italy, Japan, Mexico, Russia, Spain, US, UK)
Aug 2021

Global attitudes towards COVID-19 booster doses of vaccine were evaluated across 13 countries using an online survey. Willingness to receive a third dose was measured in 1,000 adults aged 18-74 from Canada and the US, 1,000 adults aged 16-74 from the UK, France, Germany, and Japan, and 500 adults aged 16-74 in Australia, Brazil, China, Italy, Mexico, Russia, and Spain. Results specific to Australia, Canada, UK, and US.

  • Highest intention to get a booster vaccine if it were available to respondents that day was in Brazil (96%), Mexico (93%), China (90%), Australia (82%), UK (82%), US (81%), Canada (77%), Spain (73%), Japan (72%), France (70%), Germany (70%), Italy (66%), and Russia (62%).

Canada

  • 77% of Canadians agreed that if a third dose was available today they would get it, 15% disagreed, and 9% were unsure. Wanting a booster as soon as possible was more frequent among those aged 55+ (85%).
  • 69% agreed that they will need a booster at least every year for COVID-19, 15% were unsure, and 17% disagreed.
  • Most fully vaccinated Canadians disagreed (63%) with the statement that once their country returns to pre-COVID life there isn’t a reason to get another booster shot.

US

  • 82% agreed that if a booster was available today they would get it, 10% disagreed, and 8% were unsure. Wanting a booster as soon as possible was more frequent among those aged 55+ (91%).
  • 68% agreed that they will need a booster at least every year for COVID-19, 17% were unsure, and 15% disagreed.
  • Most (60%) fully vaccinated Americans disagreed (60%) with the statement that once their country returns to pre-COVID life there isn’t a reason to get another booster shot. Agreement with not needing another booster if their country returns to pre-pandemic life was higher among those who were younger (<35) and among males.

Australia

  • 82% agreed that if a booster was available today they would get it, 13% disagreed, and 6% were unsure.
  • 70% agree that they will need a booster at least every year for COVID-19, 14% were unsure, and 15% disagreed.
  • Most fully vaccinated individuals disagreed (76%) with the statement that once their country returns to pre-COVID life there isn’t a reason to get another booster shot. Agreement with not needing another booster if their country returns to pre-pandemic life was higher among those who were younger (<35).

UK

  • 82% agreed that if a booster was available today they would get it, 11% disagreed, and 6% were unsure.
  • 77% agreed that they will need a booster at least every year for COVID-19, 11% were unsure, and 12% disagreed.
  • Most fully vaccinated individuals disagree (70%) with the statement that once their country returns to pre-COVID life there isn’t a reason to get another booster shot. Agreement with not needing another booster if their country returns to pre-pandemic life was higher among those who were younger (<35).

Abbreviations: CI, confidence interval; HCW, healthcare worker; OR, odds ratio; RR, risk ratio.

References

1

Government of Canada. COVID-19 vaccination in Canada. 2021.URL: https://health-infobase.canada.ca/covid-19/vaccination-coverage/

Return to footnote 1 referrer

2

Australian Government Department of Health. TGA approval for Pfizer COVID-19 vaccine booster dose. 2021.URL: https://www.health.gov.au/ministers/the-hon-greg-hunt-mp/media/tga-approval-for-pfizer-covid-19-vaccine-booster-dose-0

Return to footnote 2 referrer

3

UK Government. MHRA statement on booster doses of Pfizer and AstraZeneca COVID-19 vaccines. 2021.URL: https://www.gov.uk/government/news/mhra-statement-on-booster-doses-of-pfizer-and-astrazeneca-covid-19-vaccines

Return to footnote 3 referrer

4

National Advisory Committee on Immunization. Guidance on booster COVID-19 vaccine doses in Canada – Update December 3, 2021. 2021.URL: https://www.canada.ca/content/dam/phac-aspc/documents/services/immunization/national-advisory-committee-on-immunization-naci/guidance-booster-covid-19-vaccine-doses/guidance-booster-covid-19-vaccine-doses.pdf

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5

US Food & Drug Administration. Coronavirus (COVID-19) Update: FDA Expands Eligibility for Pfizer-BioNTech COVID-19 Booster Dose to 16- and 17-Year-Olds. 2021.URL: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-expands-eligibility-pfizer-biontech-covid-19-booster-dose-16-and-17#:~:text=On%20Nov.,or%20approved%20COVID%2D19%20vaccine.

Return to footnote 5 referrer

6

Government of New Zealand. Provisional Consent to the Distribution of a New Medicine. 2021.URL: https://gazette.govt.nz/notice/id/2021-go4766

Return to footnote 6 referrer

7

Institut national de santé publique du Québec. Pandémie et vaccination contre la COVID-19 - 25 janvier 2022. 2022.URL: https://www.inspq.qc.ca/covid-19/sondages-attitudes-comportements-quebecois/vaccination-25-janvier-2022

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8

Ipsos. Two in Three (67%) Canadians Believe that a Fully Vaccinated Population Won’t be Enough to Stop the Spread of Omicron. 2022.URL: https://www.ipsos.com/en-ca/news-polls/Two-Three-Canadians-Believe-Fully-Vaccinated-Population-Not-Enough-Stop-Omicron

Return to footnote 8 referrer

9

Angus Reid Institute. Kids and COVID: Half of Canadian parents with children aged 5-11 ready to vaccinate their little ones ASAP. 2021.URL: https://angusreid.org/wp-content/uploads/2021/10/2021.10.13_COVID_October_.pdf

Return to footnote 9 referrer

10

Nanos Research. A strong majority of Canadians say they will definitely take the COVID-19 vaccine booster shot when available. 2021.URL: https://nanos.co/wp-content/uploads/2022/01/2021-2045-Globe-December-Populated-Report-Booster-with-Tabs.pdf

Return to footnote 10 referrer

11

Ipsos. Global Attitudes on COVID-19 Vaccine Booster Shots. 2021.URL: https://www.ipsos.com/sites/default/files/ct/news/documents/2021-09/Global-attitudes-about-COVID-19-Vaccine-Booster-Shots-Sept%202021.pdf

Return to footnote 11 referrer

12

Office for National Statistics. Opinions and Lifestyle Survey (January 6 - January 16, 2022). 2022.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f21january2022/referencetables210122.xlsx

Return to footnote 12 referrer

13

Hahn MB, Fried RL, Cochran P, et al. Evolving perceptions of COVID-19 vaccines among remote alaskan communities. Int J Circumpolar Health. 2022 Dec;81(1):2021684. DOI:10.1080/22423982.2021.2021684.

Return to footnote 13 referrer

14

Lee RC, Hu H, Kawaguchi ES, et al. COVID-19 booster vaccine attitudes and behaviors among university students and staff: The USC trojan pandemic research initiative. medRxiv. 2021:2021.12.09.21267545. DOI:10.1101/2021.12.09.21267545.

Return to footnote 14 referrer

15

Public Health Agency of Canada. Evergreen Rapid Review on COVID-19 Vaccine Attitudes and Uptake in Canada – Update 11. 2021.URL: ocsoevidence-bcscdonneesprobantes@phac-apsc.gc.ca.

Return to footnote 15 referrer

16

Yadete T, Batra K, Netski DM, et al. Assessing acceptability of covid-19 vaccine booster dose among adult americans: A cross-sectional study. Vaccines. 2021;9(12) DOI:10.3390/vaccines9121424.

Return to footnote 16 referrer

17

Paul E, Fancourt D. Predictors of uncertainty and unwillingness to receive the COVID-19 booster vaccine: An observational study of 22,139 fully vaccinated adults in the UK. medRxiv. 2022:2021.12.17.21267941. DOI:10.1101/2021.12.17.21267941.

Return to footnote 17 referrer

18

Office for National Statistics. Opinions and Lifestyle Survey (December 15, 2021 - January 3, 2022). 2022.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f7january2022/referencetables070122.xlsx

Return to footnote 18 referrer

19

Lennon RP, Block R, J., Schneider EC, et al. PMC8650809; underserved population acceptance of combination influenza-COVID-19 booster vaccines. Vaccine. 2022 Jan 28;40(4):562-7. DOI:10.1016/j.vaccine.2021.11.097.

Return to footnote 19 referrer

20

Office for National Statistics. Vaccine Opinions Survey (September 7-16). 2022.URL: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/bulletins/coronavirusandchangingattitudestowardsvaccinationengland/7to16september2021

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21

Leger. North American Tracker - January 10th, 2022. 2022.URL: https://2g2ckk18vixp3neolz4b6605-wpengine.netdna-ssl.com/wp-content/uploads/2022/01/Legers-North-American-Tracker-January-10th-2022_V2.pdf

Return to footnote 21 referrer

22

Angus Reid Institute. Omicron Inevitability? 55% say they’ll be infected regardless of precautions; two-in-five would end all restrictions. 2022.URL: https://angusreid.org/wp-content/uploads/2022/01/2022.01.13_COVID_inevitability.pdf

Return to footnote 22 referrer

23

Angus Reid Institute. Unconcerned about Omicron: More than four-in-five now believe a COVID-19 infection would be mild, manageable. 2022.URL: https://angusreid.org/wp-content/uploads/2022/01/2022.01.26_COVID_Unconcerned_about_Omicron.pdf

Return to footnote 23 referrer

24

Pal S, Shekhar R, Kottewar S, et al. COVID-19 vaccine hesitancy and attitude toward booster doses among US healthcare workers. Vaccines. 2021;9(11) DOI:10.3390/vaccines9111358.

Return to footnote 24 referrer

25

Institut national de santé publique du Québec. Faits saillants du 11 janvier 2022. 2022.URL: https://www.inspq.qc.ca/covid-19/sondages-attitudes-comportements-quebecois/11-janvier-2022

Return to footnote 25 referrer

26

Leger. North American Tracker - August 19, 2021. 2021.URL: https://2g2ckk18vixp3neolz4b6605-wpengine.netdna-ssl.com/wp-content/uploads/2021/08/Legers-North-American-Tracker-August-19th-2021.pdf

Return to footnote 26 referrer

27

Leger. North American Tracker - December 6th, 2021. 2021.URL: https://2g2ckk18vixp3neolz4b6605-wpengine.netdna-ssl.com/wp-content/uploads/2021/12/Legers-North-American-Tracker-December-6th-2021_v2.pdf

Return to footnote 27 referrer

28

Nanos Research. Strong majority of Canadians show interest in getting a COVID-19 vaccination booster shot. 2021.URL: https://nanos.co/wp-content/uploads/2021/10/2021-1981-CTV-September-Populated-report-Powerplay-with-tabs.pdf

Return to footnote 28 referrer

29

Office for National Statistics. Coronavirus and the social impacts on Great Britain: Likelihood of a child receiving a vaccine for the coronavirus (COVID-19), 22 October 2021 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fconditionsanddiseases%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritainlikelihoodofachildreceivingavaccineforcoronaviruscovid19%2fcurrent/likelihoodofchildvaccines221021.xlsx

Return to footnote 29 referrer

30

Office for National Statistics. Coronavirus and the social impacts on Great Britain: Likelihood of a child receiving a vaccine for the coronavirus (COVID-19), 5 November 2021.

Return to footnote 30 referrer

31

Office for National Statistics. Coronavirus and the social impacts on Great Britain: 19 November 2021 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f19november2021/referencetables191121.xlsx

Return to footnote 31 referrer

32

Office for National Statistics. Coronavirus and the social impacts on Great Britain: 3 December 2021 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f3december2021/referencetables031221.xlsx

Return to footnote 32 referrer

33

Office for National Statistics. Coronavirus and the social impacts on Great Britain: attitudes to the coronavirus (COVID-19) vaccine booster and winter flu jabs (July 28 - August 1, 2021). 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritainattitudestothecoronaviruscovid19vaccineboosterandwinterflujabsreferringtotheperiod28julyto1august%2fcurrent/attitudescoronavirusvaccineboosterandflujabs0608211.xlsx

Return to footnote 33 referrer

34

Office for National Statistics. Coronavirus and the social impacts on Great Britain: attitudes to the coronavirus (COVID-19) vaccine booster and winter flu jabs (August 11 - 15, 2021). URL: https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/datasets/coronavirusandthesocialimpactsongreatbritainattitudestothecoronaviruscovid19vaccineboosterandwinterflujabsreferringtotheperiod28julyto1august/current/previous/v2/boosters20082021.xlsx

Return to footnote 34 referrer

35

Office for National Statistics. Opinions and Lifestyle Survey (August 25 - September 5, 2021). URL: https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/datasets/coronavirusandthesocialimpactsongreatbritaindata/current/previous/v75/referencetables100921.xlsx

Return to footnote 35 referrer

36

Office for National Statistics. Opinions and Lifestyle Survey (September 8 - September 19, 2021). 2021.URL: https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/datasets/coronavirusandthesocialimpactsongreatbritaindata/current/previous/v76/referencetables240921.xlsx

Return to footnote 36 referrer

37

Office for National Statistics. Opinions and Lifestyle Survey (August 18 - August 22, 2021). 2021.URL: https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/datasets/coronavirusandthesocialimpactsongreatbritaindata/current/previous/v73/referencetables200821.xlsx

Return to footnote 37 referrer

38

Office for National Statistics. Opinions and Lifestyle Survey (September 22 - October 3, 2021). 2021.URL: https://www.ons.gov.uk/file?uri=/peoplepopulationandcommunity/healthandsocialcare/healthandwellbeing/datasets/coronavirusandthesocialimpactsongreatbritaindata/current/previous/v77/referencetables081021.xlsx

Return to footnote 38 referrer

39

Office for National Statistics. Opinions and Lifestyle Survey (December 1 - December 12, 2021). 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f17december2021/referencetables171221.xlsx

Return to footnote 39 referrer

40

Office for National Statistics. Opinions and Lifestyle Survey (March 2020 - December 2021). 2021.URL: https://www.ons.gov.uk/file?uri=%2fpeoplepopulationandcommunity%2fhealthandsocialcare%2fhealthandwellbeing%2fdatasets%2fcoronavirusandthesocialimpactsongreatbritaindata%2f23december2021/opnsocialimpacts23dec.xlsx

Return to footnote 40 referrer

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