Cellulomonas biazotea - information sheet

Strain ATCC 486

Overview

The Government of Canada conducted a science-based evaluation of Cellulomonas biazotea strain ATCC 486, called a screening assessment, to address the potential for harm to Canadians and the environment.
Under the Canadian Environmental Protection Act, 1999 (CEPA 1999), the risk posed by a substance is determined by considering both its hazardous properties (its potential to cause adverse human health or ecological effects) and the amount of exposure there is to people or to the environment. A substance may have hazardous properties; however, the risk to human health or to the environment may be low depending upon the level of exposure.
- More information on assessing risk can be found in the Framework for Science-Based Risk Assessment of Micro-Organisms Regulated under the Canadian Environmental Protection Act, 1999.
In the case of Cellulomonas biazotea strain ATCC 486, the organism was estimated to have a low hazard toward both human health and the environment; and exposure to the Canadians and the environment is low. Therefore, it is concluded that Cellulomonas biazotea strain ATCC 486 is not harmful to human health or to the environment.

This screening assessment focuses on the organism Cellulomonas biazotea strain ATCC 486. This Priority C (lower hazard) organism was assessed as part of the micro-organisms initiative of the Chemicals Management Plan (CMP).
Cellulomonas biazotea strain ATCC 486 is a bacteria that could have number of consumer, commercial and industrial uses. The characterisitics of Cellulomonas biazotea strain ATCC 486 make it suitable for use in various applications including in the production of animal feed supplements, fertilizers, biodegradation, and biofuel production.
Cellulomonas biazotea strain ATCC 486 has characteristics in common with other strains of the species Cellulomonas biazotea, which are found in nature.
Based on a 2009 survey, Cellulomonas biazotea strain ATCC 486 was not reported to be manufactured in or imported into Canada.

According to information available to the Government of Canada, Canadians are not expected to be exposed to Cellulomonas biazotea strain ATCC 486 nor is it expected to be released into the Canadian environment.

There are no reports of infection, toxicity or adverse immune effects in humans specific to Cellulomonas biazotea or to the strain ATCC 486.
In the unlikely event of infection, Cellulomonas biazotea strain ATCC 486 is susceptible to clinically-relevant antibiotics.
No adverse effects in environmental species, attributed to Cellulomonas biazotea strain ATCC 486 or its close relatives, have been reported.

Considering all information presented in this assessment, the risk to human health from Cellulomonas biazotea strain ATCC 486 is low.
Also considering all information presented, there is low risk of harm to organisms and the broader integrity of the environment from Cellulomonas biazotea strain ATCC 486.
The Government of Canada published the Final Screening Assessment for Cellulomonas Biazotea Strain ATCC 486 on February 24, 2018.

As a result of this screening assessment, the Government concluded that Cellulomonas biazotea strain ATCC 486 is not harmful to human health at current levels of exposure.
The Government also concluded that Cellulomonas biazotea strain ATCC 486 is not entering the environment at levels that may be harmful to the environment.

The Government proposes that no further action under CEPA 1999 be taken on this organism in regards to potential risk to Canadians and to the environment.